NCT06205784

Prehabilitative Exercise Prior to Immobilization

Prehabilitative Exercise - Can the Physiological Consequences of Immobilization be Prevented?

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 64 (actual)
• Sponsor: Bispebjerg Hospital · Academic / Other
• Sex: All
• Age: 20 Years – 85 Years
• Healthy volunteers: Accepted

Summary

This is a 10-week human study involving 24 younger (20-35 y) and 24 older (65-85 y) healthy individuals. All participants will undergo unilateral immobilization of a knee for 7-10 days, followed by 4 weeks of heavy resistance exercise training (HReT). Half of the participants (12 younger and 12 older) will also undergo 4 weeks HReT prior to the immobilization. Prehabilitative exercise may confer protective effects on subsequent immobilization, and the various underlying mechanisms involved

Conditions

• Sarcopenia
• Skeletal Muscle Atrophy
• Disuse Atrophy

Interventions

Type	Name	Description
OTHER	Prehabilitative exercise	3-4 weeks of heavy resistance exercise

Timeline

• Start date: 2024-01-06
• Primary completion: 2025-06-01
• Completion: 2025-06-01
• First posted: 2024-01-16
• Last updated: 2025-09-19

Locations

1 site across 1 country: Denmark