NCT06196307

Early Warning and Classification Model for Acute Non-traumatic Chest Pain

A Prospective Study of Acute Nontraumatic Chest Pain - Warning and Classification

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 10,000 (estimated)
• Sponsor: Xiao-nan He · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Acute non-traumatic chest pain is one of the common causes of presentation in emergency patients, but the causes of acute non-traumatic chest pain are complex, the severity of the condition varies greatly, and the specificity of symptoms is not high. Machine learning and intelligent auxiliary models can greatly shorten the time of clinical decision-making, and improve the accuracy of etiological diagnosis in patients with chest pain, reduce the rate of misdiagnosis and missed diagnosis, and provide a clear direction for further treatment.

Detailed description

Prospective observational studies used outpatient and follow-up information to construct an auxiliary early warning model of acute non-traumatic chest pain based on federated learning, and optimized the accuracy of early warning models through retrospective and prospective studies of large cohort data, and established an efficient and stable early warning and classification model for acute non-traumatic chest pain.

Conditions

• Chest Pain

Interventions

Type	Name	Description
COMBINATION_PRODUCT	Clinical evaluation, laboratory and cardiac imaging results, medication, surgery, and any hospitalization	Examination： Electrocardiogram、 imaging examination、 X-ray, CTA, bedside echocardiography. Laboratory test results of patients, including complete blood count, D-dimer, myocardial injury markers, sST2, MPO, and other indicators. History of cardiovascular and pulmonary vascular drug therapy: Antithrombotic therapy (type, measurement) , Anticoagulation therapy (type, metering), Other drug treatments (type, measurement)

Timeline

• Start date: 2022-08-30
• Primary completion: 2027-12-30
• Completion: 2028-12-30
• First posted: 2024-01-09
• Last updated: 2026-02-05

Locations

1 site across 1 country: China

Regulatory

• FDA-regulated drug study
• FDA-regulated device study