NCT06195644

Effect of Galvanic Vestibular Stimulation on Cortical Excitability and Hand Dexterity in Multiple Sclerosis Patients

• Status: Unknown
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 40 (estimated)
• Sponsor: Cairo University · Academic / Other
• Sex: All
• Age: 20 Years – 45 Years
• Healthy volunteers: Not accepted

Summary

This study will be conducted to investigate the following: 1. The impact of implementing GVS in MS rehabilitation on cortical excitability. 2. The influence of GVS on upper limb function in patients diagnosed with MS. Patients will be randomly assigned to a control group (Conventional Physical Therapy program = CPT) and a study group (Galvanic Vestibular Stimulation = GVS in addition to the conventional program) subsequently. CPT will perform moderate intensity aerobic training (arm ergometer) and task oriented hand manipulation training, while GVS will receive Galvanic Vestibular Stimulation will be added to the conventional physical Therapy program.

Conditions

• Cortical Excitability
• Multiple Sclerosis

Interventions

Type	Name	Description
DEVICE	Galvanic vestibular stimulation	galvanic current generated by Gymna DUO 200 and delivered through conductive medium (electrode gel) by two small carbon rubber electrodes 3 cm 2 each bilaterally over two mastoid processes for 30 minutes, two times per week for 12 weeks .
DEVICE	MovAlyzeR® software from Neuroscript	MovAlyzeR® movement analysis software from Neuroscript turns a pen tablet or mouse into a high-quality system for examining movements by a pen, mouse or finger. Hence, it can train and analyze hand dexterity and handwriting using pen tablets such as sentence parameters.
DEVICE	BODYFIT Mini Portable Pedal Home Exerciser (cyclic ergometer)	stationary upper body pedaling as a moderate intensity aerobic training

Timeline

• Start date: 2023-09-03
• Primary completion: 2024-12-01
• Completion: 2025-12-01
• First posted: 2024-01-08
• Last updated: 2024-01-08

Locations

1 site across 1 country: Egypt