NCT06194006

Long Term Follow-up Grafted Huntington's Disease Patients

Long-term Follow-up of Huntington's Disease Patients Treated With Intrastriatal Fetal Neuron Allograft

• Status: Not Yet Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 39 (estimated)
• Sponsor: Assistance Publique - Hôpitaux de Paris · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Long-term follow-up of Huntington's disease patients treated with intrastriatal allografts is essential to assess the benefit/risk ratio of grafts as well as their effectiveness. Indeed, some patients are likely to develop adverse effects and the impact of alloimmunisation phenomena remains to be explored.

Detailed description

The aim is to create a specific cohort of transplant patients, to homogenise their follow-up methods, to collect all the patient data (medical, paramedical, imaging, biological) acquired from the end of their participation in MIG-HD'study (Foetal Striatal allografting in Huntington's disease: a multicentre, randomised, delayed start, phase 2 open-label cell therapy trial) until the last possible follow-up of the last patient in the study

Conditions

• Huntington Disease

Interventions

Type	Name	Description
OTHER	Follow-up	Follow-up grafted patients as long as their condition allows

Timeline

• Start date: 2024-01-01
• Primary completion: 2034-01-01
• Completion: 2034-01-01
• First posted: 2024-01-08
• Last updated: 2024-01-08

Locations

1 site across 1 country: France