Clinical Trials Directory

Trials / Unknown

UnknownNCT06193278

Individual Neuromodulation for PDS

Personalized Neuromodulation Treatment for Parkinson's Syndrome

Status
Unknown
Phase
N/A
Study type
Interventional
Enrollment
60 (estimated)
Sponsor
Ruijin Hospital · Academic / Other
Sex
All
Age
40 Years – 80 Years
Healthy volunteers
Not accepted

Summary

Parkinsonian Syndromes (PDS) with predominant motor dysfunction include progressive supranuclear palsy (PSP), multiple system atrophy (MSA) and corticobasal degeneration (CBD). Current treatment options for PDS are extremely limited due to the less understanding of disease pathophysiology and lack of therapeutic targets. Combining the results of previous studies and our group's previous research, sixty qualified PDS patients would be enrolled to conduct a prospective single-center randomized sham controlled clinical trial to verify the new therapeutic options that can improve symptoms and effectively slow the progression of the disease.

Conditions

Interventions

TypeNameDescription
DEVICENeuromodulationNoninvasive brain stimulation (NIBS) includes a variety of noninvasive neuromodulation techniques such as transcranial magnetic stimulation (TMS), transcranial direct current stimulation (TDCS), and so on. Theta burst stimulation(TBS) is a new form of excitatory or inhibitory rTMS treatment that is less time-consuming and more effective than traditional rTMS in a single treatment session.

Timeline

Start date
2023-09-01
Primary completion
2025-05-31
Completion
2025-06-30
First posted
2024-01-05
Last updated
2024-01-10

Locations

1 site across 1 country: China

Source: ClinicalTrials.gov record NCT06193278. Inclusion in this directory is not an endorsement.