NCT06191380

Effects of Cycling and Virtual Reality on Thinking Speed in Persons With MS (PACE-MS)

Effects of a Single Bout of Moderate Intensity Aerobic Cycling Exercise Combined With Virtual Reality on Processing Speed in Persons With Multiple Sclerosis and Mobility Disability

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 23 (actual)
• Sponsor: Kessler Foundation · Academic / Other
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

To compare the effects of cycling exercise with different types of virtual reality on processing/thinking speed in persons with multiple sclerosis (MS).

Detailed description

The purpose of this research study is to learn how different types of cycling exercise can improve short-term processing speed, or speed of thinking, in persons with MS. In this study, we will compare the effects of cycling alone to cycling with two different types of virtual reality. Participants will complete all three cycling conditions, one per week. We are studying these types of cycling because there are currently no effective treatment options to improve processing speed in persons with MS and combining exercise with virtual reality is a promising technique.

Conditions

• Multiple Sclerosis

Interventions

Type	Name	Description
BEHAVIORAL	PACE-MS	A single bout of cycling.

Timeline

• Start date: 2024-02-12
• Primary completion: 2025-10-28
• Completion: 2025-10-28
• First posted: 2024-01-05
• Last updated: 2025-10-30

Locations

1 site across 1 country: United States