NCT06189144

Testing an Intervention in Irritative Contact Dermatitis

Testing the Effectiveness of an Intervention in Irritative Contact Dermatitis:Randomized Controlled Trial

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 25 (estimated)
• Sponsor: University of Split, School of Medicine · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Accepted

Summary

An eczematous reaction is an inflammatory intolerance response of the skin. In acute phase the reaction is characterized by erythema and blistering while in the chronic phase it presents as dryness, itchiness and lichenification. Irritative contact dermatitis describes these patterns of reaction in response to toxicity of chemicals on the skin cells, which trigger inflammation by activation of the innate immune system.

Detailed description

An eczematous reaction is an inflammatory intolerance response of the skin. In acute phase the reaction is characterized by erythema and blistering while in the chronic phase it presents as dryness, itchiness and lichenification. Irritative contact dermatitis describes these patterns of reaction in response to toxicity of chemicals on the skin cells, which trigger inflammation by activation of the innate immune system. Therefore, the aim of this study was to see if omega cream, as proposed by its mechanism of action, could improve SLS induced contact dermatitis.

Conditions

• Contact Dermatitis
• Contact Dermatitis Irritant

Interventions

Type	Name	Description
OTHER	Emollient cream treatment	Rilastil Difesa Sterile cream
OTHER	no treatment	no treatment

Timeline

• Start date: 2023-06-01
• Primary completion: 2024-06-01
• Completion: 2024-06-01
• First posted: 2024-01-03
• Last updated: 2024-01-03

Locations

1 site across 1 country: Croatia