NCT06188767

Testosterone-induced Muscle Memory and Underlying Mechanisms

Long-term Effects of Anabolic Androgenic Steroids on Muscle Growth Potential: Testosterone-induced Muscle Memory and Underlying Mechanisms

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 30 (estimated)
• Sponsor: Morten Hostrup, PhD · Academic / Other
• Sex: Male
• Age: 18 Years – 40 Years
• Healthy volunteers: Accepted

Summary

The purpose of this project is to investigate underlying mechanisms of testosterone- and resistance training-induced muscle hypertrophy and muscle memory in humans.

Conditions

• Skeletal Muscle Physiology

Interventions

Type	Name	Description
DRUG	Testosterone Undecanoate	Following testosterone/placebo injection, participants undergo supervised resistance training for 4 weeks. This period is followed by a washout period with no drug and either continued resistance training or detraining for 16 weeks. Thereafter, another 4-week period with supervised resistance training is commenced, with no drug.

Timeline

• Start date: 2025-04-01
• Primary completion: 2027-12-01
• Completion: 2028-12-01
• First posted: 2024-01-03
• Last updated: 2025-04-10

Locations

1 site across 1 country: Denmark