NCT06188546

Propofol for Prophylaxis of Morphine Induced Pruritis in Caesarean Section

Administration of Propofol for Prophylaxis of Intrathecal Morphine Induced Pruritus in Caesarean Section

• Status: Unknown
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 200 (estimated)
• Sponsor: Assiut University · Academic / Other
• Sex: Female
• Age: 20 Years – 40 Years
• Healthy volunteers: Accepted

Summary

the goal of this randomized clinical trial is to find the optimum sub hypnotic dose of iv propofol that prevents the incidence of itching induced from intrathecal morphine used in spinal anesthesia in caesarean section operation. the main questions it aim to answer are the number of patients complained of pruritus in the first 24 hours post operative period and the severity of the pruritus. participants will be divided into 4 groups. 1st group receives 0 mg of propofol , 2nd receives 10 mg , 3rd receives 20 mg and the 4th receives 30 mg.

Conditions

• Pruritus Caused by Drug

Interventions

Type	Name	Description
DRUG	Propofol	trying different dosages of propofol 10mg/ml IV to determine the prophylactic dose for morphine induced pruritis

Timeline

• Start date: 2024-01-01
• Primary completion: 2025-01-01
• Completion: 2025-03-01
• First posted: 2024-01-03
• Last updated: 2024-01-03

Regulatory

• FDA-regulated drug study