NCT06187532

Carotid Plaque-Burden Scale and Outcomes. A Real Life Study

Carotid Plaque-Burden Scale and Outcomes. Improvements in Risk Stratification for Future Cardiovascular Disease by Adding to SCORE2. A Real Life Study

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 1,004 (actual)
• Sponsor: Fundación para la Formación e Investigación de los Profesionales de la Salud de Extremadura · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

Carotid ultrasonography has been proposed as a tool for prediction of future cardiovascular disease (CVD). Nevertheless, its role in clinical practice remains controversial. Methods: The investigators analyse the incidence of CVD and mortality in a cohort of 1004 participants without preexisting CVD according to a simple plaque scale recorded in different segments of the carotid artery assess by ultrasound. A prognostic tool for CV events was development adding Carotid Plaque-Burden (CPB) scale to the Systematic COronary Risk Evaluation (SCORE2) table (CPB- SCORE2 scale).

Detailed description

Based in number of plaques and stenosis a simple plaque scale was recorded in different segments of carotid artery, involving a cohort of 1004 participants with vascular risk factors. Outcomes were recorded during 14 years. A prognostic tool for CV events was development adding simple Carotid Plaque-Burden (CPB) scale to the SCORE2 table (CPB- SCORE2 scale).

Conditions

• Atheroscleroses, Cerebral
• Carotid Plaque

Timeline

• Start date: 2000-02-02
• Primary completion: 2023-04-03
• Completion: 2023-12-07
• First posted: 2024-01-02
• Last updated: 2024-02-12