NCT06186245

Starvation in the Treatment of Diabetic Ketoacidosis

Starvation in the Treatment of Diabetic Ketoacidosis: Is There Enough Evidence to Support This Practice?

• Status: Enrolling By Invitation
• Phase: N/A
• Study type: Interventional
• Enrollment: 200 (estimated)
• Sponsor: Texas Tech University Health Sciences Center · Academic / Other
• Sex: All
• Age: 18 Years – 89 Years
• Healthy volunteers: Accepted

Summary

Diabetic ketoacidosis (DKA) and hyperosmolar hyperglycemic state (HHS) are common, but serious metabolic disorders are often encountered in intensive care. In the intensive care setting, it is common to withhold food from patients during treatment of DKA. However, there is no evidence or current literature supporting this practice. The following proposed research investigates the initiation of an early diet versus withholding food during the treatment of diabetic ketoacidosis.

Conditions

• Diabetes Mellitus
• Diabetic Ketoacidosis

Interventions

Type	Name	Description
OTHER	Early feeding with an oral diet	Participants in the treatment arm will be initiated on a clear liquid diet on day 1 of medical ICU admission. Diet will be progressed on day 2 to full liquid diet or diabetic diet as patient tolerates based on which diet the patient would prefer.

Timeline

• Start date: 2023-12-27
• Primary completion: 2025-11-01
• Completion: 2025-12-01
• First posted: 2023-12-29
• Last updated: 2025-08-19

Locations

1 site across 1 country: United States