NCT06186115

Intraarticular Gold Microparticles for Hip Osteoarthritis

Intraarticular Gold Microparticles for Hip Osteoarthritis - a 2-year Follow-up Pilot Study.

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 20 (estimated)
• Sponsor: Northern Orthopaedic Division, Denmark · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: —

Summary

In a pilot study, the investigators recently showed that intraarticular metallic gold microparticles reduce knee osteoarthritis pain for up to two years and found associated significant proteomic changes in serum and synovial fluid within eight weeks. This study aim to evaluate the outcome after intra-articular injection of gold microparticles for hip osteoarthritis.

Detailed description

A cohort of 20 patients, aged ≥ 18 years, with pain ≥ 3 months, and Kellgren-Lawrence OA grade 2-4, will beincluded. Metallic gold 20 mg, 72.000 pieces, 20-40 µ-meter (Berlock-Micro-Implants, HumanGoldInject) (1) were injected into the hip joint using hyaluronic acid as the carrier. In total, we treated 24 hip joints. The primary outcome was the Western Ontario and McMaster Universities Arthritis Index (WOMAC).

Conditions

• Osteoarthritis, Hip

Interventions

Type	Name	Description
COMBINATION_PRODUCT	Gold	Intra articular

Timeline

• Start date: 2024-03-04
• Primary completion: 2024-04-01
• Completion: 2024-05-01
• First posted: 2023-12-29
• Last updated: 2024-01-30

Locations

1 site across 1 country: Denmark