NCT06185595

Effect of Glycerol-Electrolyte Beverages on Fluid Balance in Healthy Euhydrated Men and Women at Rest

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 37 (actual)
• Sponsor: PepsiCo Global R&D · Industry
• Sex: All
• Age: 18 Years – 50 Years
• Healthy volunteers: Accepted

Summary

The objective of this study is to determine the effect of consumption of drinks with varying amounts of glycerol and electrolytes on fluid balance at rest.

Conditions

• Hydration

Interventions

Type	Name	Description
OTHER	Beverage. Incomplete block where each participant will complete 3 of the 6 possible glycerol-sodium blends in random order.	9.3 oz (273 ml) aliquot of one of the study beverages every 15 min for a total of 28 oz (828 ml) over a 45-min period, followed by 15 min of rest. Flavored water matched for sweetness, color. flavor, but cannot be matched for saltiness. All sodium-containing drinks will include a base blend of other electrolytes (potassium 15 mmol/L, magnesium 8 mmol/L, and calcium 5 mmol/L).

Timeline

• Start date: 2024-01-08
• Primary completion: 2024-06-28
• Completion: 2024-06-28
• First posted: 2023-12-29
• Last updated: 2025-01-03

Locations

1 site across 1 country: United States