Trials / Recruiting
RecruitingNCT06184646
Elucidating the Minimal Effective Dose of Prunes for Bone Health in Postmenopausal Women
Effect of Calcium and Vitamin D Supplements and/or Prunes on Bone Health
- Status
- Recruiting
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 200 (estimated)
- Sponsor
- San Diego State University · Academic / Other
- Sex
- Female
- Age
- —
- Healthy volunteers
- Not accepted
Summary
The objective of this study is to examine if calcium and vitamin D supplements and/or prune can prevent bone loss in postmenopausal women.
Detailed description
Two hundred randomly assigned to one of two treatment groups: 1) 30 g prunes and 2) control (0 g prunes). Both groups received 500 mg calcium and 400 IU Vitamin D as a daily supplement. Blood samples are collected at baseline, 12 and 24 months to assess biomarkers of bone turnover. Physical activity recall and food records are obtained at baseline, 12 and 24 months to examine physical activity and dietary confounders as potential covariates. Dual-energy x-ray absorptiometry (DXA) and peripheral quantitative computed tomography (pQCT) will be completed at baseline, 12 and 24 months to examine bone mineral density and structure.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DIETARY_SUPPLEMENT | Prune | 30 g of prune/day |
Timeline
- Start date
- 2024-03-15
- Primary completion
- 2028-12-01
- Completion
- 2028-12-01
- First posted
- 2023-12-28
- Last updated
- 2025-07-02
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT06184646. Inclusion in this directory is not an endorsement.