NCT06183450

Hearing and Cognition in Aging Adults

• Status: Not Yet Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 262 (estimated)
• Sponsor: University Hospital, Toulouse · Academic / Other
• Sex: All
• Age: 45 Years – 50 Years
• Healthy volunteers: Accepted

Summary

This cohort study is expected to provide valuable insights into the complex interplay between auditory and cognitive functions and how they change over time. The results of this study will have important implications for the prevention, diagnosis, and treatment of age-related hearing and cognitive disorders

Detailed description

The aim of the study is to identify the early perceptual and cognitive alterations related to age-related hearing loss or presbycusis, establish a correlation between the degree of hearing loss and the deterioration of cognitive functions, and examine the effectiveness of hearing loss management in reversing observed cognitive impairments. This project has the potential to shed light on the importance of early detection of hearing impairments in preventing cognitive decline. The data collected from this cohort, rigorously assessed for both auditory and cognitive functions, could serve as the basis for several high-level scientific investigations.

Conditions

• Presbycusis

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	auditory level	* Evaluation of auditory thresholds through audiometric tests. * Evaluation of speech comprehension in noise through a vocal audiometry test in noise (FraMatrix). * Evaluation of spatial auditory behavior and spatial precision using a spatial discrimination test (Minimum Audible Angle) and a static sound localization test in virtual reality.
DIAGNOSTIC_TEST	cognitive level	* Evaluation of attention and short-term memory functions with verbal and non-verbal tasks: Digit Span Test and Reading Span Test. * Evaluation of inhibition capacities using the Stroop Test. * Evaluation of executive functions, visual attention, reasoning, and mental arithmetic using the Raven's Matrix test.
DIAGNOSTIC_TEST	quality of life level	\- Evaluation of quality of live level via Speech, Spatial and Qualities of Hearing Scale (SSQ-12) and EuroQol-5D questionnaires.

Timeline

• Start date: 2024-01-01
• Primary completion: 2033-01-01
• Completion: 2033-01-01
• First posted: 2023-12-27
• Last updated: 2023-12-27

Locations

1 site across 1 country: France