NCT06182657

The Prognostic Value of the Degree of Pathological Response of Induction Chemotherapy for NPC

The Prognostic Value of the Degree of Pathological Response at One Cycle of Induction Chemotherapy for Locally Advanced Nasopharyngeal Carcinon-a Prospective Observational Study

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 300 (estimated)
• Sponsor: Jiangxi Provincial Cancer Hospital · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This study aims to explore the prognostic value of pathological remission after one cycle of induction chemotherapy in locally advanced nasopharyngeal carcinoma, and the change of immune micro-environment after one cycle induction chemotherapy, including the density of immune cells infiltration and tertiary lymphoid structures.

Conditions

• Nasopharyngeal Carcinoma
• Pathologic Complete Response
• Tumor Microenvironment

Timeline

• Start date: 2024-01-01
• Primary completion: 2027-06-30
• Completion: 2029-06-30
• First posted: 2023-12-27
• Last updated: 2024-02-08

Locations

1 site across 1 country: China