Trials / Recruiting
RecruitingNCT06182215
PostoperAtive Neurocognitive Dysfunction After Major AbdomiNal Surgery (PANDAMAN)
Postoperative Neurocognitive Dysfunction After Major Abdominal Surgery: A Prospective Observational Cohort Study
- Status
- Recruiting
- Phase
- —
- Study type
- Observational
- Enrollment
- 500 (estimated)
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University · Academic / Other
- Sex
- All
- Age
- 65 Years – 90 Years
- Healthy volunteers
- Not accepted
Summary
Predisposing and precipitating factors for perioperative delirium for the elderly remain elusive. This research will be conducted to determine risk factors of postoperative delirium.
Detailed description
This study intends to include 500 participants over 65 years old undergoing elective abdominal major surgery. The primary outcome is incidence of delirium at 7 days postoperatively, and the secondary outcomes include preoperative sleep disorders(Athens In-somnia Scale, AIS), postoperative cognitive impairment (Abbreviated Mental Test Score, AMTS), postoperative pain (NRS pain score), incidence of significant postoperative complications, length of hospital stay, and serum biomarkers levels.
Conditions
Timeline
- Start date
- 2023-12-11
- Primary completion
- 2025-12-31
- Completion
- 2026-12-31
- First posted
- 2023-12-26
- Last updated
- 2024-06-17
Locations
1 site across 1 country: China
Source: ClinicalTrials.gov record NCT06182215. Inclusion in this directory is not an endorsement.