NCT06182111

Intraoperative Administration of Intravenous Morphine in Patients Undergoing Laparoscopic Cholecystectomy

Intraoperative Administration of Intravenous Morphine in Patients Undergoing Laparoscopic Cholecystectomy - a Retrospective, Observational, Quality-improvement Study

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 300 (estimated)
• Sponsor: Esbjerg Hospital - University Hospital of Southern Denmark · Academic / Other
• Sex: All
• Age: 21 Years
• Healthy volunteers: —

Summary

The goal of this observational, quality improvement study is to compare the effect of a dose of morphine given during gall-bladder removal surgery. The main questions to answer are: * Do participants, who are given given a dose of morphine during gall-bladder removal surgery, experience less pain after surgery? * Does a dose of morphine during gall-bladder removal surgery cause more side effects? The investigators will compare the effects of two types of anesthesia: a) anesthesia without morphine during surgery, and b) anesthesia with morphine during surgery.

Detailed description

The investigators will use Redcap secure web application (via Open Patient Data Explorative Network, a subsidiary under University Hospital of Odense, Denmark) for data collection and data management. No sample size has been collected as per the observational design. The investigators expect to include an equal number in each study arm, as there has been no indication of change in indications for surgery type. The investigators expect to use students T-test for comparison of groups. If possible logistic regression analyses will be undertaken.

Conditions

• Postoperative Pain
• Morphine
• Laparoscopic Cholecystectomy

Interventions

Type	Name	Description
PROCEDURE	Intraoperative morphine	Morphine dose = 0,1 mg mg/kg (maximum 10 mg) intravenous given 20 min after start of surgery

Timeline

• Start date: 2024-06-01
• Primary completion: 2025-05-31
• Completion: 2025-10-31
• First posted: 2023-12-26
• Last updated: 2024-08-28

Locations

1 site across 1 country: Denmark