NCT06182007

Post-Resuscitation Pneumothorax - Analysis of Incidence, Risk Factors and Outcome Relevance

Pneumothorax After Cardiopulmonary Resuscitation Following Out-of-Hospital Cardiac Arrest - Analysis of Incidence, Risk Factors and Impact on Outcome

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 237 (actual)
• Sponsor: Auinger, Daniel MD · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: —

Summary

In this retrospective study, the investigators seek to investigate the incidence of pneumothorax following possible risk factors, and elucidate its association with outcomes.

Detailed description

This is a retrospective analysis of routine data, collected by a single Emergency Medical System (EMS). Adult patients (≥18 years) hospitalised after Out-of-Hospital Cardiac Arrest (OHCA) who received chest compressions and underwent chest imaging within 12 hours after hospital admission were included. Variables and outcomes ascertained are built up of the core elements of the latest version of the Utstein Resuscitation Registry Template for OHCA. This includes sex, age, aetiology of arrest, response times of the first emergency medical service team and emergency physician, witnessed cardiac arrest, bystander CPR/AED, arrest location, first monitored rhythm, defibrillation time, drugs given, reperfusion attempted and target temperature management. Additional variables studied were pre-existing health status represented by the Pre Emergency Status Assessment (PESA), history of lung disease, no-flow-time (time from collapse until initiation of CPR), use of a mechanical chest compression device and prehospital CPR duration. The primary outcome is incidence of pneumothorax, secondary outcomes are survival to hospital discharge and favourable neurological condition at hospital discharge defined by a cerebral performance category (CPC) of 1 or 2.

Conditions

• Cardiac Arrest
• Pneumothorax
• Resuscitation

Interventions

Type	Name	Description
PROCEDURE	Cardiopulmonary Resuscitation	Cardiopulmonary Resuscitation (Advanced Life Support) according to current guidelines

Timeline

• Start date: 2020-02-02
• Primary completion: 2022-10-20
• Completion: 2022-12-31
• First posted: 2023-12-26
• Last updated: 2023-12-26

Locations

1 site across 1 country: Austria