NCT06179420

The Effectiveness of Advanced Decision Support Tool (OPT-IVF) for IVF Treatment

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 30 (estimated)
• Sponsor: National University of Malaysia · Academic / Other
• Sex: Female
• Age: 18 Years – 45 Years
• Healthy volunteers: Accepted

Summary

This prospective study is subject to approval of institutional medical research ethics committee. Patient undergoing second cycle IVF will be enrolled into the intervention group. Intervention involved using a clinical decision support tool, Opt-IVF to guide gonadotrophins dosing and trigger dates for a personalized controlled ovarian stimulation cycle based on the distribution of follicle sizes on day 1 and day 5, and hormone dosages given on day 1 to 4. Patients will undergo transvaginal ultrasound exam on day 1 and day 5 of the cycle to determine the number and size of follicles present. The data is used in the Opt-IVF decision support tool to suggest Gonadotropin dosage for D5 and beyond and to recommend the antagonist start day and trigger day. Clinical investigators will not override the Opt-IVF recommended dosage in any patients.

Detailed description

The total dosage of gonadotrophin, number of good quality oocytes and blastocyst will be analyzed from each arm.

Conditions

• Fertility Issues

Interventions

Type	Name	Description
OTHER	total cumulative gonadotrophin usage	total dosage in IU

Timeline

• Start date: 2024-03-13
• Primary completion: 2026-01-31
• Completion: 2026-01-31
• First posted: 2023-12-21
• Last updated: 2024-03-15

Locations

1 site across 1 country: Malaysia