NCT06178848

EEG Parameters Between Remimazolam- and Propofol-based Anesthesia

Comparison of Quantitative EEG Parameters During Anesthesia Emergence Between Remimazolam Group and Propofol Group

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 60 (actual)
• Sponsor: Yonsei University · Academic / Other
• Sex: All
• Age: 19 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

This is an observational study comparing perioperative quantitative EEG parameters between the conventional propofol/remifentanil and remimazolam/remifentanil. We aim to compare and analyze the differences in EEG patterns during the postoperative recovery in a group that underwent remimazolam and remifentanil-based total intravenous anesthesia(TIVA), in comparison to propofol and remifentanil-based TIVA

Conditions

• Cholecystitis, Acute
• Gallbladder Neoplasms
• Acalculous Cholecystitis

Interventions

Type	Name	Description
DRUG	propofol group	During induction, the propofol group initiates with a target-controlled infusion (TCI) of propofol, starting at an effect site concentration of 4.0 ng/ml. After intubation, it is adjusted to maintain an appropriate depth of anesthesia based on the EEG (psi target 40).
DRUG	remimazolam group	The remimazolam group begins with a continuous infusion of remimazolam at 6 mg/kg/hr, which is then adjusted to 1 mg/kg/hr after loss of consciousness to maintain an appropriate depth of anesthesia based on the EEG (psi target 40).

Timeline

• Start date: 2023-06-26
• Primary completion: 2023-10-27
• Completion: 2023-10-27
• First posted: 2023-12-21
• Last updated: 2023-12-21

Locations

1 site across 1 country: South Korea