NCT06174259

Influence of Intermittent Fasting on Locally Advanced Breast Cancer Patients

Influence of Intermittent Fasting on Locally Advanced Breast Cancer Patients: a Prospective Randomized Controlled Trial

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 66 (estimated)
• Sponsor: Menoufia University · Academic / Other
• Sex: Female
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Breast cancer is the most common cancer type among women in Egypt and world. Preclinical studies show fasting reduces growth factors and modulates nutrient sensing systems, protecting normal cells against chemotherapy. However, cancer cells are not protected due to Differential Stress Resistance (DSR), making them more vulnerable to chemotherapeutics. This study aims to evaluate intermittent fasting impact on neoadjuvant chemotherapy in breast cancer patients.

Conditions

• Locally Advanced Breast Cancer
• Intermittent Fasting

Interventions

Type	Name	Description
OTHER	intermittent fasting	16/8 intermittent fasting (limiting foods and calorie-containing beverages to a set window of 8 hours per day)

Timeline

• Start date: 2023-06-01
• Primary completion: 2024-06-01
• Completion: 2025-06-01
• First posted: 2023-12-18
• Last updated: 2024-02-01

Locations

1 site across 1 country: Egypt