Trials / Recruiting
RecruitingNCT06173401
Comparing SingLe- Vs Multi-Fraction Spine STereotActic Radiosurgery in Spinal Metastases
A Randomized Phase III TriaL Comparing SingLe- Versus Multi-Fraction Spine STereotActic Radiosurgery for Patients With Spinal Metastases (ALL-STAR)
- Status
- Recruiting
- Phase
- Phase 3
- Study type
- Interventional
- Enrollment
- 274 (estimated)
- Sponsor
- Stanford University · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
The goal of this study is to determine whether fractionated Stereotactic radiosurgery (SRS) for spine metastases is associated with improved local tumor control compared to single-fraction SRS. Patients will be randomized to treatment with spine SRS using either 22 Gy in 1 fraction or 28 Gy in 2 fractions.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| RADIATION | Single-fraction spine SRS | Treatment Arm 1: Single-fraction spine SRS (22 Gy x 1) |
| RADIATION | Multi-fraction spine SRS | Treatment Arm 2: Multi-fraction spine SRS (14 Gy x 2) |
Timeline
- Start date
- 2023-12-18
- Primary completion
- 2028-12-01
- Completion
- 2028-12-01
- First posted
- 2023-12-15
- Last updated
- 2025-07-16
Locations
1 site across 1 country: United States
Regulatory
- FDA-regulated device study
Source: ClinicalTrials.gov record NCT06173401. Inclusion in this directory is not an endorsement.