NCT06171204

The Use of Stromal Vascular Fraction for Knee Arthrosis

Gebruik Van Stromale Vasculaire Fractie Uit Vetweefsel Na Invriezing Voor Knie Arthrose

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 10 (estimated)
• Sponsor: University Hospital, Ghent · Academic / Other
• Sex: All
• Age: 18 Years – 90 Years
• Healthy volunteers: Accepted

Summary

A trial to investigate the safety and efficacy of SVF for the treatment of knee arthrosis. Patients will undergo a single liposuction to obtain the SVF. The SVF will then be isolated and frozen in our laboratory. The SVF will then be injected up to 2 times into the fat pad of the patient's knee.

Detailed description

Stromal Vascular Fraction (SVF) from adipose tissue is increasingly being used in the clinic for a variety of conditions (skin disorders, joint pain, etc.). SVF is a collective term for cells that can be obtained from liposuction fat. These cells can be separated from the fat by mechanical processing of the liposuction fat combined with an additional centrifugation. Despite the fact that enough SVF can be isolated after such a liposuction for multiple treatments (\>3), our research group has found a way to safely freeze SVF without significant loss of SVF cells. In this way, a patient would only have to undergo one liposuction and associated anesthesia to be able to obtain multiple SVF treatments.

Conditions

• Knee Arthrosis

Interventions

Type	Name	Description
PROCEDURE	Injection of SVF in fat pad of the knee	Knee fat pad injection with SVF at orthopaedics/physical medicine outpatient clinic

Timeline

• Start date: 2022-09-19
• Primary completion: 2025-12-31
• Completion: 2026-12-31
• First posted: 2023-12-14
• Last updated: 2024-11-08

Locations

1 site across 1 country: Belgium