NCT06168123

Future Optimal Research and Care Evaluation - Aortic Stenosis

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 800 (estimated)
• Sponsor: St. Antonius Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 110 Years
• Healthy volunteers: Not accepted

Summary

In the past decade the treatment of aortic valve stenosis has rapidly changed. At first, transcatheter aortic valve implantation (TAVI) was a last resort option for inoperable patients. Nowadays, it more and more becomes an alternative to surgical aortic valve replacement (SAVR) - also in younger and lower risk patients. This poses important questions to clinical practise regarding the optimal life-time management of each individual patient. Which involves (durability of) treatment modality (surgical vs. transcatheter vs. conservative treatment) as well as the duration and type of the required antithrombotic treatment. Objective: to evaluate the effect of treatment modality (surgical vs. transcatheter vs. conservative treatment) and its complications on quality of life and survival in AoS patients.

Conditions

• Severe Aortic Valve Stenosis
• Moderate Aortic Valve Stenosis

Interventions

Type	Name	Description
BEHAVIORAL	Quality of life questionnaires will be assessed in addition to standard care	Quality of life questionnaires will be assessed in addition to standard care

Timeline

• Start date: 2023-11-27
• Primary completion: 2027-08-01
• Completion: 2027-08-01
• First posted: 2023-12-13
• Last updated: 2024-12-03

Locations

1 site across 1 country: Netherlands