Trials / Recruiting
RecruitingNCT06167174
Exploring Biomarkers for Therapeutic Response of Lupus Nephritis Based on Multi Omics Analysis
Exploring Biomarkers for Therapeutic Response of Lupus Nephritis Based on Multi Omics
- Status
- Recruiting
- Phase
- —
- Study type
- Observational
- Enrollment
- 100 (estimated)
- Sponsor
- Chinese SLE Treatment And Research Group · Academic / Other
- Sex
- All
- Age
- 16 Years – 60 Years
- Healthy volunteers
- Accepted
Summary
This is an observational study of patients with lupus nephritis aiming to find biomarkers that can predict patients' response to immunosuppressants. We planed to collect 100 lupus nephritis patients' peripheral blood,kidney tissues and urine before and after treatment (mycophenolate mofetil or cyclophosphamide, in combination with glucocorticoids). Then multi omics analysis, including single cell RNA-seq, ATAC-seq and CITE-seq, will be performed to find new biomarkers for patients' response and prognosis.
Conditions
Timeline
- Start date
- 2023-12-05
- Primary completion
- 2027-12-05
- Completion
- 2028-12-05
- First posted
- 2023-12-12
- Last updated
- 2023-12-12
Locations
1 site across 1 country: China
Source: ClinicalTrials.gov record NCT06167174. Inclusion in this directory is not an endorsement.