NCT06165887

The Relationship Between Moderate-to-severe Psoriasis and Sleep Disturbance

The Relationship Between Moderate-to-severe Psoriasis and Sleep Disturbance: a Prospective Cohort Study

• Status: Not Yet Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 156 (estimated)
• Sponsor: Shanghai Yueyang Integrated Medicine Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Accepted

Summary

Psoriasis is a common chronic and systemic immune-mediated disease, induced by a combination of genetic and environmental effects. The increasingly worrying question is the negative impact on patients' sleep, which has become an important comorbidity of psoriasis. To investigate the causal relationship between psoriasis and sleep status, a prospective cohort study will be conducted by separating moderate-to-severe psoriasis patients and healthy individuals into distinct cohorts in order to observe their sleep status.

Detailed description

Target follow-up duration for the study is 24 weeks, during which participants will undergo a sleep monitoring session every 8 weeks. The sleep monitoring data collected includes time to fall asleep, time to bed, sleep perception, and the Pittsburgh Sleep Quality Index (PSQI). The Dermatology Quality of Life Index (DLQI), the Psoriasis Area and Severity Index (PASI), and the Visual Analog Scale (VAS) will simultaneously be used to assess the severity of the disease in the cohort of patients with psoriasis.

Conditions

• Moderate-to-severe Psoriasis

Interventions

Type	Name	Description
OTHER	No intervention	This is an observational study, no intervention will be implemented.
OTHER	No intervention	This is an observational study, no intervention will be implemented.

Timeline

• Start date: 2024-02-01
• Primary completion: 2026-06-01
• Completion: 2026-06-01
• First posted: 2023-12-12
• Last updated: 2024-02-21

Locations

1 site across 1 country: China