NCT06165289

Endoscopic Balloon Dilatation Combined With PRP Injection in Colonic Stenosis in Crohn's Disease

Efficacy and Safety of Endoscopic Balloon Dilatation Combined With Autologous Platelet-rich Plasma (PRP) Injection in Colonic Stenosis in Crohn's Disease

• Status: Enrolling By Invitation
• Phase: N/A
• Study type: Interventional
• Enrollment: 74 (estimated)
• Sponsor: Sixth Affiliated Hospital, Sun Yat-sen University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The aim was to investigate whether endoscopic balloon dilatation combined with PRP injection can help prevent or prolong restenosis in patients with Crohn's disease with colonic stenosis, and to explore the concentration of PRP. The study was a single-center, randomized, non-controlled study. Experimental group of patients underwent endoscopic balloon dilation and submucosal injection of PRP at the wound edge, historical control was used, and the patients included in the study were randomly divided into high concentration group and low concentration group.

Conditions

• Crohn Disease

Interventions

Type	Name	Description
OTHER	PRP Injection	Endoscopic balloon dilatation combined with autologous platelet-rich plasma (PRP) injection with different concerntrations

Timeline

• Start date: 2024-03-01
• Primary completion: 2026-12-31
• Completion: 2026-12-31
• First posted: 2023-12-11
• Last updated: 2026-01-14

Locations

1 site across 1 country: China