NCT06165042

Silver Diamine Fluoride in Molar-Incisor Hypomineralisation

Evaluation of Silver Diamine Fluoride Application in Molar-Incisor Hypomineralisation-Affected Molars

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 34 (actual)
• Sponsor: Marmara University · Academic / Other
• Sex: All
• Age: 8 Years – 13 Years
• Healthy volunteers: Accepted

Summary

The objective of this study is to assess the efficacy of silver diamine fluoride application in molars affected by molar-incisor hypomineralization. Additionally, the study aims to evaluate the effectiveness of the combined application of silver diamine fluoride, commonly used for dentin hypersensitivity, with a glass hybrid restorative system. The goal is to mitigate sensitivity and improve chewing functions in teeth affected by molar-incisor hypomineralization.

Detailed description

In a research study focusing on 120 children aged 8-13 with molar incisor hypomineralization (MIH), a comprehensive examination of 240 teeth will be conducted. Study will employ selective caries removal to eliminate decay and subsequently apply restorations. The two intervention groups are delineated as follows: Group 1: Glass hybrid restorative system (Equia Forte, GC Europe, Leuven, Belgium) Group 2 : Restoration involving fluoride varnish (SDI Riva Star) + glass hybrid restorative system (Equia Forte, GC Europe, Leuven, Belgium)

Conditions

• Molar-Incisor Hypomineralisation

Interventions

Type	Name	Description
OTHER	glass hybrid restorative system	In the teeth where the indication is identified, selective caries removal will be performed to eliminate the decayed tooth tissue. Subsequently, for each patient in the study apply glass hybrid restorative system (Equia Forte, GC Europe, Leuven, Belgium)
OTHER	Fluoride varnish + Glass hybrid restorative system	In the teeth where the indication is identified, selective caries removal will be performed to eliminate the decayed tooth tissue. Subsequently, for each patient in the study apply Fluoride varnish (SDI Riva Star)+ Glass hybrid restorative (Equia Forte, GC Europe, Leuven, Belgium)

Timeline

• Start date: 2024-04-01
• Primary completion: 2024-12-26
• Completion: 2025-01-30
• First posted: 2023-12-11
• Last updated: 2026-04-06

Locations

1 site across 1 country: Turkey (Türkiye)