NCT06164015

3D Ultrasound to Assess in Recurrent Miscarriage

Association of Acquired Uterine Abnormalities With Recurrent Miscarriage

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 400 (estimated)
• Sponsor: University Hospitals of Derby and Burton NHS Foundation Trust · Academic / Other
• Sex: Female
• Age: 18 Years – 40 Years
• Healthy volunteers: Accepted

Summary

This observational study aims to compare the prevalence of acquired abnormalities of the uterus (fibroids, polyps, intrauterine adhesions, adenomyosis) in women who have recurrent miscarriages with the fertile population.

Detailed description

High-quality studies including several meta-analyses have proven the association between congenital uterine anomalies and recurrent miscarriages. Nevertheless, there are limited studies evaluating the impact of acquired uterine anomalies on recurrent miscarriages. This prospective observational study will aim to compare the prevalence of acquired uterine anomalies between the study group and the control group. The secondary aim will be to compare the Endometrial morphological features like endometrial volume, endometrial and sub-endometrial vascularity between the two groups

Conditions

• Recurrent Miscarriage

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	3D Ultrasound scan with power Doppler angiography	The study group and the control group will be offered a 3D ultrasound scan as a part of this trial.

Timeline

• Start date: 2023-12-01
• Primary completion: 2025-12-31
• Completion: 2025-12-31
• First posted: 2023-12-11
• Last updated: 2023-12-11