NCT06162403

Exploring the Benefit of Peripheral Nerve Stimulation in Treating Pain From Chemo-induced Peripheral Neuropathy: A Longitudinal Single Center Feasibility Study

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 10 (estimated)
• Sponsor: M.D. Anderson Cancer Center · Academic / Other
• Sex: All
• Age: 18 Years – 85 Years
• Healthy volunteers: Not accepted

Summary

To learn if peripheral nerve stimulation (PNS) can help to improve pain in participants with CIPN.

Detailed description

Primary objective: To assess Pain intensity (NRS) scores in chemotherapy induced peripheral neuropathy (CIPN) participants before and after use of peripheral nerve stimulation (PNS). Secondary objectives: To assess changes in quantitative sensory testing (QST), gait testing, and skin punch biopsy to compare the integrity of Meissner's corpuscles (MC), pain disability using the Oswestry Disability Index (ODI), pain interference using the Brief Pain Inventory (BPI), and Patient Global Impression of Change (PGIC) in CIPN patients before and after use of PNS.

Conditions

• Peripheral Nerve Stimulation
• Chemotherapy-induced Peripheral Neuropathy

Interventions

Type	Name	Description
OTHER	Peripheral Nerve Stimulation	The leads are inserted through a needle. If needed, the study team may give participants anesthetic (for example, as a cream/gel on your skin and/or as an injection) to numb the area where the leads will be injected.

Timeline

• Start date: 2024-02-22
• Primary completion: 2027-12-31
• Completion: 2027-12-31
• First posted: 2023-12-08
• Last updated: 2026-02-19

Locations

1 site across 1 country: United States