Clinical Trials Directory

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UnknownNCT06158945

The Role of Endothelin 1 as a Marker of Renal Impairment in Sickle Cell Disease

Status
Unknown
Phase
Study type
Observational
Enrollment
30 (estimated)
Sponsor
Sohag University · Academic / Other
Sex
All
Age
1 Year – 18 Years
Healthy volunteers
Accepted

Summary

Sickle cell disease (SCD) refers to a group of hemoglobinopathies that include mutations in the gene encoding the beta subunit of hemoglobin. Within the umbrella of SCD, many subgroups exist, namely sickle cell anemia (SCA), hemoglobin SC disease (HbSC), and hemoglobin sickle-beta-thalassemia (beta-thalassemia positive or beta-thalassemia negative). Several other minor variants within the group of SCDs also, albeit not as common as the varieties mentioned above. It is essential to mention the sickle cell trait (HbAS), which carries a heterozygous mutation and seldom presents clinical signs or symptoms. Sickle cell anemia is the most common form of SCD

Conditions

Interventions

TypeNameDescription
DIAGNOSTIC_TESTurinary endothelin 1assesment of endothelin 1 in urinary sample

Timeline

Start date
2023-10-24
Primary completion
2024-10-23
Completion
2024-10-23
First posted
2023-12-06
Last updated
2023-12-06

Locations

1 site across 1 country: Egypt

Source: ClinicalTrials.gov record NCT06158945. Inclusion in this directory is not an endorsement.