NCT06155539

A Study of Blood Metabolic Markers in Patients With Type 2 Diabetes Mellitus of Different Stages

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 105 (estimated)
• Sponsor: Peng Wu · Academic / Other
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

Metabolomics is an emerging "omics" after genomics, transcriptomics and proteomics, which can reflect the physiological state of organisms more directly and accurately. Whether metabolite differences exist in patients with type 2 diabetes of different stages and whether such metabolite differences can be used as potential markers have not yet been studied, which is of great significance to explore. In this study, 105 patients with different stages of type 2 diabetes mellitus were enrolled according to the inclusion and exclusion criteria, and the metabolites in the samples were detected by ultra-high performance liquid chromatography coupled with tandem time-of-flight mass spectrometry (UHPLC-Q-TOF MS) after the blood samples were collected, and the corresponding investigative data were collected, and then baseline and demographic analyses, metabolomics data processing, and analysis of the results were carried out to provide a reference for the identification of metabolic markers and to provide a reference for the identification of significant metabolic markers in diabetic patients.

Conditions

• Diabetes Mellitus, Type 2

Interventions

Type	Name	Description
OTHER	No intervention	No intervention

Timeline

• Start date: 2024-01-01
• Primary completion: 2025-05-31
• Completion: 2025-12-31
• First posted: 2023-12-04
• Last updated: 2023-12-04

Locations

1 site across 1 country: China