Trials / Recruiting
RecruitingNCT06152497
The Role of Histamine in Muscle Protein Synthesis Following Resistance Training
The Role of Histamine in Muscle Protein Synthesis Following Chronic Resistance Training
- Status
- Recruiting
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 50 (estimated)
- Sponsor
- University Ghent · Academic / Other
- Sex
- Male
- Age
- 18 Years – 45 Years
- Healthy volunteers
- Accepted
Summary
Blocking histamine H1/H2 receptors blunts chronic endurance training adaptations. The current study addresses the following research question: "What is the influence of histamine H1 signaling on training adaptations following ten weeks of resistance training in human skeletal muscle." Results from this study will yield more insights into the molecular mechanisms of adaptations to exercise training.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Placebo | Oral placebo |
| DRUG | H1 blockade: Telfast: 180mg Fexofenadine | H1 blockade: oral blockade with 180mg Fexofenadine |
| BEHAVIORAL | Resistance training | Resistance training: lower body exercise |
Timeline
- Start date
- 2023-09-01
- Primary completion
- 2026-12-31
- Completion
- 2026-12-31
- First posted
- 2023-11-30
- Last updated
- 2023-12-13
Locations
1 site across 1 country: Belgium
Source: ClinicalTrials.gov record NCT06152497. Inclusion in this directory is not an endorsement.