NCT06151405

Nutrition for Asthmatics

Individualized Nutrition to Help Asthmatics Improve Lung Function and Energetics (INHALE)

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 15 (estimated)
• Sponsor: Pennington Biomedical Research Center · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

Determine to what extent three distinct dietary approaches improve asthma control and lung function.

Detailed description

This is a crossover design pilot trial that will recruit 15 adults with asthma. Participants will undergo screening and a lead-in period before being randomized to a series of three, 7-day diets with a 7+ day washout period between each diet. Asthma control and lung function will be assessed at the completion of each diet. The goal of this pilot trial is to understand the effect of diet on asthma and conduct an exploratory analysis on factors that may predict the response to diet.

Conditions

• Asthma

Interventions

Type	Name	Description
OTHER	DGA Diet	A fully provisioned isocaloric, isonitrogenous study diet following the Dietary Guidelines for Americans (DGA) Including: * A variety of vegetables and fruits * Grains, at least half of which are whole grains * Fat-free or low-fat dairy * A variety of protein foods, including seafood, lean meats and poultry, eggs, legumes, nuts, and seeds * This healthy eating pattern also limits saturated fats and trans fats, added sugars, and sodium.
OTHER	MCT Diet	A fully provisioned isocaloric, isonitrogenous study diet following the Dietary Guidelines for Americans supplemented with medium chain triglycerides (MCT).
OTHER	KETO Diet	A fully provisioned isocaloric, isonitrogenous ketogenic study diet.

Timeline

• Start date: 2024-07-17
• Primary completion: 2026-12-31
• Completion: 2027-03-01
• First posted: 2023-11-30
• Last updated: 2024-09-19

Locations

1 site across 1 country: United States