NCT06151002

PD Frontline (Part of RAPSODI GD) Remote Assessment of People With Parkinson's

PD Frontline, Part of RAPSODI GD (Remote Assessment of Parkinsonism Supporting Ongoing Development of Interventions in Gaucher's Disease) to Build an Online Trial-ready Cohort of GBA Genotyped People With Parkinson's

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 4,800 (estimated)
• Sponsor: University College London Hospitals · Academic / Other
• Sex: All
• Age: 18 Years – 90 Years
• Healthy volunteers: —

Summary

PD Frontline (part of RAPSODI GD) is an online study observational study with the goal of bringing People with Parkinson's to the frontline of research by getting them trial ready. To do this, participants are offered genetic sequencing for the GBA and LRRK2 gene with an at-home saliva collection kit.

Detailed description

PD Frontline is an online one-time questionnaire based study with the purpose of identifying potential candidates for gene targeted trials and observational studies. Once the questionnaire is completed, the participant is sent a saliva collection kit in the post to provide a sample for genetic testing. The genes tested for are GBA1, the most common risk factor gene for Parkinson's, and LRRK2. Once tested, the participant is informed of their results and kept up-to-date with any studies or trials for which they may be eligible.

Conditions

• Parkinson Disease

Timeline

• Start date: 2020-02-15
• Primary completion: 2025-02-14
• Completion: 2040-08-20
• First posted: 2023-11-30
• Last updated: 2023-11-30

Locations

1 site across 1 country: United Kingdom