NCT06149936

Excimer Light(308) Therapy for Resistant Alopecia Areata

Efficacy of Excimer Light(308) Therapy for Resistant Alopecia Areata

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 20 (estimated)
• Sponsor: Assiut University · Academic / Other
• Sex: All
• Age: 18 Years – 55 Years
• Healthy volunteers: —

Summary

This study aimed to evaluate the efficacy and safety of the 308-nm excimer lamp in resistant AA treated with topical minoxidil .

Detailed description

Alopecia areata (AA) is a chronic, nonscarring, T-cell mediated autoimmune disease, presenting with localized or diffuse hair fall in hair-bearing areas. Approximately 1.7% of the population experience an episode of AA during their lifetime. Both sexes are equally affected, and most new cases are recorded below the age of 30 years . Excimer laser using high-dose monochromatic UV radiation can trigger apoptosis and induce immunological suppression through altering cytokine production such as IL-4, IL-10, prostaglandin E2, platelet-activating factor, and cis-urocanic acid. Benefits have only been seen with localized patches of AA, and regrowth of hair occurs only in treated areas .

Conditions

• Alopecia Areata

Interventions

Type	Name	Description
DEVICE	excimer light	Excimer laser using high-dose monochromatic UV radiation

Timeline

• Start date: 2023-12-01
• Primary completion: 2024-11-30
• Completion: 2024-12-30
• First posted: 2023-11-29
• Last updated: 2023-11-29