NCT06149078

The Relationship of Serum Uric Acid With Severity of Knee Osteoarthritis

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 150 (estimated)
• Sponsor: Sohag University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

Osteoarthritis (OA) is the most prevalent form of arthritis. Its pathogenesis remains poorly understood. Though historically regarded as a disease of mechanical degeneration, it is now appreciated that inflammation plays an important role in OA pathogenesis (Krasnokutsky et al., 2017). The hallmark of OA is the degradation and loss of articular cartilage, although most tissues of the joint become affected, such as bone, synovium, ligaments, menisci (knee), labrum (hip), periarticular fat, and muscle (Englund, 2023).It is believed that there is a pathological link between hyperuricemia and OA Therefore, we conducted a cross-sectional study to evaluate an association between elevated SUA and radiographic OA of the knee) Bipan Shrestha, 2019 (.

Conditions

• Knee Osteoarthritis

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	serum uric acid	to detect the relaton ship of serum uric acid with sevwrity of knee osteoarthritis

Timeline

• Start date: 2023-12-10
• Primary completion: 2024-05-10
• Completion: 2024-05-10
• First posted: 2023-11-28
• Last updated: 2023-11-28

Locations

1 site across 1 country: Egypt