NCT06148207

[18F]BF3-BPA Injection for PET Imaging Study of Gliomas in the Brain

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 80 (estimated)
• Sponsor: Huashan Hospital · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

In this clinical study, we proposed to perform \[18F\]BF3-BPA PET imaging in subjects with gliomas, to observe the binding ability and non-specific binding of the tracer to glioma lesions in vivo, and at the same time to evaluate the effectiveness of \[18F\]BF3-BPA in the diagnosis and differential diagnosis of glioma, and to evaluate the tolerability and safety of the tracer and the imaging method. The efficacy of \[18F\]BF3-BPA in the diagnosis and differential diagnosis of gliomas will be evaluated, as well as the tolerability and safety of this tracer and imaging method. This study will provide a new method for in vivo imaging of gliomas and provide a clear and intuitive imaging basis for clinical diagnosis, differential diagnosis and treatment.

Conditions

• Cerebral Gliosis
• Positron Emission Tomography

Interventions

Type	Name	Description
RADIATION	[18F]BF3-BPA Injection for PET Imaging	Two dosing dose groups were designed, 5±1 mCi or 9±1 mCi, with 20 subjects in each dose group, and the high dose group study was conducted after enrollment in the low dose group was completed.

Timeline

• Start date: 2023-09-01
• Primary completion: 2025-06-13
• Completion: 2025-09-01
• First posted: 2023-11-28
• Last updated: 2023-11-28

Locations

1 site across 1 country: China