Trials / Completed
CompletedNCT06148129
Immunohistochemistry Role in Better Prognosis of Endometrial Carcinoma Patients
Stratification of Endometrial Carcinoma Patients Using Immunohistochemistry for Better Surgical Planning and Prognosis
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 96 (actual)
- Sponsor
- Zagazig University · Other Government
- Sex
- Female
- Age
- 36 Years – 72 Years
- Healthy volunteers
- Not accepted
Summary
The incidence of endometrial cancer (EC) is increasing .Different risk classifications are used to direct the primary and adjuvant therapy. The European Society for Medical Oncology - European Society of Gynaecological Oncology -European Society for Radiotherapy \& Oncology (ESMO-ESGO- ESTRO) could guide the need for lymph node surgery pre-operatively, and also post-operatively to determine adjuvant treatment. Low-risk patients are managed with surgery alone, while higher-risk group patients undergo more aggressive surgical options. So, it is important to identify new prognostic markers for better stratification of patients to avoid under- or over treatment of EC patients.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DIAGNOSTIC_TEST | Tissue Biopsy | The Post-hysterectomy tissue biopsy was analyzed immunohistochemically for detection of estrogen and progesterone receptors, P53 and L1CAM |
Timeline
- Start date
- 2019-01-12
- Primary completion
- 2021-10-01
- Completion
- 2022-03-01
- First posted
- 2023-11-28
- Last updated
- 2023-11-28
Locations
1 site across 1 country: Egypt
Source: ClinicalTrials.gov record NCT06148129. Inclusion in this directory is not an endorsement.