NCT06146855

Amnion Membrane Versus DFGG Using the Tunneling Technique in Management of Gingival Recession Defects.

Amnion Membrane as a Soft Tissue Substitute Versus De- Epithelialized Free Gingival Graft Using the Tunneling Technique in Management of Gingival Recession Defects: A Randomized Controlled Clinical Trial.

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 22 (estimated)
• Sponsor: Cairo University · Academic / Other
• Sex: All
• Age: 18 Years – 60 Years
• Healthy volunteers: Accepted

Summary

Treatment of gingival recession is indicated mainly for esthetic reasons and keratinized tissue augmentation (Zucchelli and Mounssif, 2015). An array of surgical techniques has been proposed by the literature to cover gingival recession defects with well-documented successful outcomes. The selection of one technique over the other depends on many factors. Some of these factors are related to the gingival recession defect itself, others are related to the anatomy of the palatal fibromucosa, or related to the patient variabilities (Zucchelli and De Sanctis, 2000). Controversy exists in the literature regarding the patient morbidity after connective tissue graft harvesting. Inconclusive postulations have been made about the post-operative patient morbidity outcomes and root coverage outcomes when comparing connective tissue graft harvesting in comparison to allograft membranes used for root coverage. The use of connective tissue graft in combination with root coverage techniques remain the gold standard for root coverage procedures. The problem with the connective tissue graft is that harvesting a graft from the palate increases morbidity, needs an extra surgical site which is more traumatic for the patient, depends on the donor tissue which could be limited, increases surgical chair-time and needs increased surgical skills (Cortellini \& Pini Prato 2012). The rationale behind the use of amnion membrane is to avoid the morbidity inherent with connective tissue graft harvesting.

Conditions

• Gingival Recession

Interventions

Type	Name	Description
PROCEDURE	Tunneling procedure with Amnion Membrane	Root Coverage by tunneling procedure with the addition of Amnion Membrane as a soft tissue substitute
PROCEDURE	Tunneling procedure with De-epithelialized Free Gingival Graft	Root Coverage by tunneling procedure with the addition of De-epithelialized Free Gingival Graft

Timeline

• Start date: 2024-02-05
• Primary completion: 2024-12-01
• Completion: 2024-12-01
• First posted: 2023-11-27
• Last updated: 2024-02-13

Locations

1 site across 1 country: Egypt