NCT06146413

Triggering Oocyte Maturation in Normoresponders Using Double Trigger or HCG Trigger

Triggering Oocyte Maturation in Normoresponders Using Double Trigger or HCG Trigger . A Randomized Controlled Trial

• Status: Unknown
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 150 (estimated)
• Sponsor: Bedaya Hospital · Academic / Other
• Sex: Female
• Age: 18 Years – 40 Years
• Healthy volunteers: Not accepted

Summary

The aim of this study is to compare the efficacy double trigger \[ co-administration of GnRH agonist with HCG 40 and 34 h prior to ovum pick-up, respectively\] with HCG trigger in inducing oocyte maturation.

Detailed description

Several studies revealed that the double trigger regimen was effective in the treatment of patients with a history of immature oocytes retrieved or with suboptimal oocytes yield. The investigators designed this randomized controlled trial to compare the efficacy double trigger with HCG trigger in inducing oocyte maturation.in normoreponders undergoing IVF-ET

Conditions

• Infertility

Interventions

Type	Name	Description
DRUG	Double trigger	GnRH agonist ( Triptorelin ) ( 0.2 mg / S.C ) and hCG ( 10000 IU) are administered 40 and 34 h before ovum pick-up
DRUG	HCG trigger	hCG ( 10000 IU) is administered 36 h before ovum pick-up

Timeline

• Start date: 2023-12-30
• Primary completion: 2025-03-30
• Completion: 2025-12-30
• First posted: 2023-11-24
• Last updated: 2023-11-29

Locations

1 site across 1 country: Egypt