NCT06146296

THE EFFECT OF VITAMIN C ON POST-ORTHODONTIC TREATMENT RELAPSE

THE EFFECT OF VITAMIN C ON POST-ORTHODONTIC TREATMENT RELAPSE: A RANDOMIZED CONTROLLED CLINICAL TRIAL

• Status: Unknown
• Phase: Phase 2 / Phase 3
• Study type: Interventional
• Enrollment: 36 (estimated)
• Sponsor: Nourhan M.Aly · Academic / Other
• Sex: All
• Age: 19 Years – 25 Years
• Healthy volunteers: Not accepted

Summary

The aim of this study is to evaluate and compare the effect of locally injected and orally administered (systemic) Vitamin C on post-orthodontic treatment relapse

Conditions

• Orthodontic Relapse

Interventions

Type	Name	Description
BIOLOGICAL	Local Vitamin C injection	An injection of 1-1.5 ml of L-ascorbic acid, locally introduced in relation to the keratinized gingival tissues, with extension to the whole target region successively. The injected area will be massaged for equal distribution of the injected vitamin. Injections will be performed on the first day of retainer delivery (T0), after 1 month (T1), after 3 months (T2), and after 6 months (T3). Hence, a total of 4 local Vit-C injections will be performed over the study period.
BIOLOGICAL	Oral Vitamin C supplement	Patients will be prescribed a daily oral (systemic) Vit-C supplement to be taken over the follow up period.

Timeline

• Start date: 2023-11-01
• Primary completion: 2024-06-01
• Completion: 2024-06-01
• First posted: 2023-11-24
• Last updated: 2023-11-24

Locations

1 site across 1 country: Egypt