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Trials / Active Not Recruiting

Active Not RecruitingNCT06144840

INcreased Sun Exposure Without Pain In Research Participants With EPP or XLP

A Phase 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate Efficacy, Safety, and Tolerability of MT-7117 in Adults and Adolescents With Erythropoietic Protoporphyria or X-Linked Protoporphyria

Status
Active Not Recruiting
Phase
Phase 3
Study type
Interventional
Enrollment
165 (actual)
Sponsor
Tanabe Pharma America, Inc. · Industry
Sex
All
Age
12 Years – 75 Years
Healthy volunteers
Not accepted

Summary

To investigate the efficacy of MT-7117 on time to onset and severity of first prodromal symptoms (burning, tingling, itching, or stinging) associated with sunlight exposure in adults and adolescents with EPP or XLP.

Conditions

Interventions

TypeNameDescription
DRUGDersimelagonMT-7117
DRUGPlaceboPlacebo

Timeline

Start date
2023-12-11
Primary completion
2026-04-01
Completion
2026-06-01
First posted
2023-11-22
Last updated
2025-12-11

Locations

36 sites across 11 countries: United States, Australia, Bulgaria, Czechia, France, Italy, Japan, Netherlands, Poland, Spain, United Kingdom

Regulatory

Source: ClinicalTrials.gov record NCT06144840. Inclusion in this directory is not an endorsement.