Trials / Withdrawn
WithdrawnNCT06144827
A Pilot Study For Patients Receiving Radiation Therapy for Liver Cancer
Pilot Study to Assess the Role of Blood-based Biomarkers and Quantitative MR Imaging for Patients Receiving Radiation Therapy for Liver Cancer
- Status
- Withdrawn
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 0 (actual)
- Sponsor
- Montefiore Medical Center · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
The purpose of this study is to evaluate the role of quantitative MR imaging and blood-based biomarkers to measure liver function in patients receiving radiation therapy for liver cancer or cancer that has spread to the liver.
Detailed description
The purpose of this study is to evaluate the role of quantitative MR imaging and blood-based biomarkers to measure liver function in patients receiving radiation therapy for liver cancer or cancer that has spread to the liver. The feasibility of using MR imaging to monitor liver function at baseline and following liver radiation therapy will be determined. Information from MR images and blood samples, along with patient questionnaires, will be used.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DEVICE | Multiparametric MRI scans | Multiparametric MRI scans will be used to evaluate baseline degree of liver fibroinflammation and function as well as temporal changes in liver fibroinflammation and function using MRI-based LiverMultiScan software. We will also measure liver function using HepQuant SHUNT test in a subset of patients enrolled in this study. |
| DEVICE | Multiparametric MRI scans + HepQuantShunt Test | Eligible patients can have previously undergone any modality and number of prior treatments for their hepatic malignancies, must be considered for either liver photon or proton radiation in the de-novo or re-irradiation setting and can be simultaneously enrolled on parallel trials. Patients must not have any contraindications that would preclude MRI imaging or receipt of HepQuant SHUNT test for those agreeable to have HepQuant SHUNT test. |
Timeline
- Start date
- 2025-01-01
- Primary completion
- 2028-01-01
- Completion
- 2028-01-01
- First posted
- 2023-11-22
- Last updated
- 2025-03-18
Regulatory
- FDA-regulated device study
Source: ClinicalTrials.gov record NCT06144827. Inclusion in this directory is not an endorsement.