Trials / Not Yet Recruiting
Not Yet RecruitingNCT06144112
Fibrinogen Concentrates Versus Cryoprecipitate in Liver Transplant Surgery
A Randomized Trial Comparing the Time for Managing Intraoperative Hypofibrinogenemia Using Fibrinogen Concentrates Versus Cryoprecipitate in Liver Transplant Surgery (FIBCRYO-LT Trial)
- Status
- Not Yet Recruiting
- Phase
- Phase 4
- Study type
- Interventional
- Enrollment
- 92 (estimated)
- Sponsor
- Konkuk University Medical Center · Academic / Other
- Sex
- All
- Age
- 20 Years – 75 Years
- Healthy volunteers
- Accepted
Summary
We compared the time consumed for goal-directed management of hypofibrinogemia using two strategies during liver transplant (LT) surgery: a conventional cryoprecipitate-based strategy versus a lyophilized fibrinogen concentrate-based strategy
Detailed description
The primary outcome is an inter-group comparison of treatment time (T-time, the duration from ordering cryoprecipitate or FC to completing its administration). The secondary measures include comparisons of perioperative bleeding, blood transfusion, coagulation profiles, reoperation, thromboembolic complications, mortality, oxygenation profiles, fibrinolysis phenotypes, and costs for bleeding management and length of hospital stay.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| BIOLOGICAL | fresh frozen plasma | transfusion of fresh frozen plasma |
| BIOLOGICAL | prothrombin complex concentrate | prothrombin complex concentrate administration |
Timeline
- Start date
- 2025-09-01
- Primary completion
- 2026-03-31
- Completion
- 2026-03-31
- First posted
- 2023-11-22
- Last updated
- 2025-07-20
Locations
1 site across 1 country: South Korea
Source: ClinicalTrials.gov record NCT06144112. Inclusion in this directory is not an endorsement.