NCT06143696

QXZS in Menopausal Syndrome Based on 16S rRNA Sequencing Technology

Study on the (Heart) Brain-gut Axis Mechanism of Qingxin Zishen Decoction in Treating Hot Flashes in Menopausal Syndrome Based on 16S rRNA Sequencing Technology

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 60 (estimated)
• Sponsor: Yun Chen · Academic / Other
• Sex: Female
• Age: 45 Years – 55 Years
• Healthy volunteers: Not accepted

Summary

The goal of this clinical trial is to explore the differences of intestinal flora and saliva flora between menopausal women, and the changes after medication, to find the association between the two and menopausal syndrome. The main questions it aims to answer are: * What are the differences in intestinal flora and saliva flora in menopausal women with hot flashes and sweating. * Whether these differences change after using traditional Chinese medicine and the association between intestinal, salivary flora and menopausal syndrome. 60 patients will be screened according to the clinical experimental criteria. They will be randomly divided into trial group (30 cases) and control group (30 cases). The test group takes traditional Chinese medicine Qingxin Zishen decoction, and the control group takes oral Femoston, comparing the two groups with analysis of symptom improvement, intestinal flora and salivary flora with 16S rRNA sequencing technology.

Conditions

• Menopause

Interventions

Type	Name	Description
DRUG	Qingxin Zishen decoction	Oral administration, 1 dose daily, twice a day
DRUG	Femoston	Oral administration, 1 pill each time, once a day

Timeline

• Start date: 2023-08-01
• Primary completion: 2024-08-31
• Completion: 2025-06-30
• First posted: 2023-11-22
• Last updated: 2023-11-22

Locations

1 site across 1 country: China