NCT06142656

Efficacy of Vildagliptin Versus Metformin in Poly Cystic Ovary Syndrome

Efficacy of Vildagliptin Versus Metformin in Poly Cystic Ovary Syndrome: A Randomized Clinical Trial

• Status: Recruiting
• Phase: Phase 2 / Phase 3
• Study type: Interventional
• Enrollment: 60 (estimated)
• Sponsor: October 6 University · Academic / Other
• Sex: Female
• Age: 18 Years – 50 Years
• Healthy volunteers: Not accepted

Summary

Polycystic ovary syndrome (PCOS) is an endocrine disorder that affects approximately 10-20% of women of reproductive age, Management strategies for PCOS include lifestyle modifications such as diet and physical activity that are the first-line approach to treatment; however, they are reported to be minimally effective in reducing weight or treating PCOS-related symptoms.Pharmacological options are also available; however, they are not explicitly approved for PCOS treatment as they have been primarily used to treat other conditions such as T2DM

Conditions

• Poly Cystic Ovary Syndrome

Interventions

Type	Name	Description
DRUG	Metformin Hydrochloride tablet	Metformin Hydrochloride 850 mg oral tablet
DRUG	Vildagliptin 50 MG	Vildagliptin 50 MG oral tablets

Timeline

• Start date: 2023-11-25
• Primary completion: 2025-12-01
• Completion: 2026-02-01
• First posted: 2023-11-21
• Last updated: 2025-07-30

Locations

1 site across 1 country: Egypt