NCT06141447

Changes in Hemorrhage With Prophylactic Oxytocin for Dilation and Evacuation

Changes in Rate of Hemorrhage With Prophylactic Oxytocin for Second Trimester Dilation and Evacuation in the Clinic Setting

• Status: Recruiting
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 150 (estimated)
• Sponsor: University of Colorado, Denver · Academic / Other
• Sex: Female
• Age: 18 Years – 55 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to assess the effectiveness of prophylactic oxytocin on hemorrhage rates for second trimester dilation and evacuation (D\&E) in the clinic setting.

Conditions

• Hemorrhage

Interventions

Type	Name	Description
DRUG	Oxytocin + normal saline	40 units IV oxytocin once in a 1000 mL bag of normal saline
DRUG	Normal saline	1000 mL bag of normal saline alone

Timeline

• Start date: 2024-05-02
• Primary completion: 2026-11-02
• Completion: 2026-11-02
• First posted: 2023-11-21
• Last updated: 2024-12-10

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated drug study