NCT06139861

Better Sleep Study

A Confirmatory Efficacy Trial of Engaging a Novel Sleep/Circadian Rhythm Target as Treatment for Depression in Adolescents

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 200 (estimated)
• Sponsor: University of California, San Francisco · Academic / Other
• Sex: All
• Age: 12 Years – 18 Years
• Healthy volunteers: Not accepted

Summary

The overall aim of this proposal is a confirmatory efficacy trial sufficiently powered and designed to test the hypothesis that improving the relationship between biological circadian timing and waketime, a novel modifiable target, improves depression outcomes in a subgroup of adolescents with depression and a misaligned relationship between biological circadian timing and waketime utilizing a cognitive-behavioral sleep intervention.

Conditions

• Depression in Adolescence
• Delayed Sleep Phase

Interventions

Type	Name	Description
BEHAVIORAL	TranS-C	Transdiagnostic Sleep and Circadian Intervention (TranS-C) is an evidence based cognitive-behavioral sleep therapy.
BEHAVIORAL	Psychoeducation	The overarching principle is to provide information about how sleep, stress, diet, health, exercise, accidents and mood are inter-related and have reciprocal effects.

Timeline

• Start date: 2024-03-15
• Primary completion: 2028-08-01
• Completion: 2028-08-01
• First posted: 2023-11-18
• Last updated: 2025-07-08

Locations

1 site across 1 country: United States